Altered motor nerve excitability in end-stage kidney disease
نویسندگان
چکیده
منابع مشابه
Altered motor nerve excitability in end-stage kidney disease.
Although multiple toxins have been implicated in the development of uraemic neuropathy, no causative agent has been identified. In the present study, the excitability properties of lower limb motor nerves in patients with end-stage kidney disease treated with haemodialysis were measured before, during and after a standard 5 h haemodialysis session, in an attempt to explore the pathophysiology o...
متن کاملEffects of Hemodiafiltration and High Flux Hemodialysis on Nerve Excitability in End-Stage Kidney Disease
OBJECTIVES Peripheral neuropathy is the most common neurological complication in end-stage kidney disease. While high flux hemodialysis (HFHD) and hemodiafiltration (HDF) have become the preferred options for extracorporeal dialysis therapy, the effects of these treatments on nerve excitability have not yet been examined. METHODS An observational proof-of-concept study of nerve excitability a...
متن کاملIschaemia induces paradoxical changes in axonal excitability in end-stage kidney disease.
Peripheral neuropathy is present in 65% of patients with end-stage kidney disease (ESKD). No cause is yet established: nerve excitability studies have shown that axons are chronically depolarized, primarily owing to hyperkalaemia, but in vitro studies have suggested a role for axonal Na+/K+ pump dysfunction. To investigate Na+/K+ pump activity in vivo, lower limb ischaemia was induced in five E...
متن کاملCardiorenal Syndrome in End-Stage Kidney Disease.
BACKGROUND Cardiorenal syndrome (CRS) in patients with end-stage kidney disease (ESKD) represents mainly cardiovascular disease (CVD) due to various complications associated with renal dysfunction-defined as type 4 CRS by Ronco et al.-because the effect of cardiac dysfunction on the kidneys does not need to be taken into consideration, unlike in non-dialysis dependent chronic kidney disease (CK...
متن کاملCardiorenal Syndrome in End-Stage Kidney Disease
Background: Cardiorenal syndrome (CRS) in patients with end-stage kidney disease (ESKD) represents mainly cardiovascular disease (CVD) due to various complications associated with renal dysfunction—defined as type 4 CRS by Ronco et al.—because the effect of cardiac dysfunction on the kidneys does not need to be taken into consideration, unlike in non-dialysis dependent chronic kidney disease (C...
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ژورنال
عنوان ژورنال: Brain
سال: 2005
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awh558